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almost old news but how do people feel about changing the mechanics of the human body? We are not talking about replacing the part with a mechanical equivalent we are talking about improving the processes to achieve the same goals.

Quote from National Geographics December 2011 ''it's time to look past biomimicry. Wings that flap didn't help mankind fly, so why must a substitute heart beat like a natural one? Mother Nature did the best she could''

http://abcnews.go.com/Health/texas-man-pioneers-beatless-heart-wave-future/story?id=13838596#.TtfXjFZDolo
huh ... cool!
I wasn't aware this was news as such. I thought this was already developed more than ten years ago, but it seems I was wrong.
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godspeeed: almost old news but how do people feel about changing the mechanics of the human body? We are not talking about replacing the part with a mechanical equivalent we are talking about improving the processes to achieve the same goals.

Quote from National Geographics December 2011 ''it's time to look past biomimicry. Wings that flap didn't help mankind fly, so why must a substitute heart beat like a natural one? Mother Nature did the best she could''

http://abcnews.go.com/Health/texas-man-pioneers-beatless-heart-wave-future/story?id=13838596#.TtfXjFZDolo
Those sorts of substitutions are risky. Sometimes it's a matter of that's how it could be done with organs, but even in those cases you have to worry about the rest of the body, not just what you're replacing.

In this case I would be concerned about the effects that would have on the circulatory system, specifically the way that the body handles changes in temperature. A beatless heart valve would deprive the arteries of the regular work out they adjusting to variable blood pressure and it turns out that that's very important. Basically one of the ways in which the body adjusts to the temperature is by expanding and restricting blood flow to the skin.
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hedwards: In this case I would be concerned about the effects that would have on the circulatory system, specifically the way that the body handles changes in temperature
Could be somewhat similar to side effect of this.
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godspeeed: almost old news but how do people feel about changing the mechanics of the human body? We are not talking about replacing the part with a mechanical equivalent we are talking about improving the processes to achieve the same goals.

Quote from National Geographics December 2011 ''it's time to look past biomimicry. Wings that flap didn't help mankind fly, so why must a substitute heart beat like a natural one? Mother Nature did the best she could''

http://abcnews.go.com/Health/texas-man-pioneers-beatless-heart-wave-future/story?id=13838596#.TtfXjFZDolo
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hedwards: Those sorts of substitutions are risky. Sometimes it's a matter of that's how it could be done with organs, but even in those cases you have to worry about the rest of the body, not just what you're replacing.

In this case I would be concerned about the effects that would have on the circulatory system, specifically the way that the body handles changes in temperature. A beatless heart valve would deprive the arteries of the regular work out they adjusting to variable blood pressure and it turns out that that's very important. Basically one of the ways in which the body adjusts to the temperature is by expanding and restricting blood flow to the skin.
do you think the body would adapt and find another way?
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godspeeed: do you think the body would adapt and find another way?
It likely would, the problem is that there isn't any certainty. That and we're not sure what the adaptation might be, how long it would take or if there's a population that couldn't handle it. We know that if we replace a body part with one that functions identically what we're dealing with, but if you substitute something that doesn't then it's really hard to say what the consequences of that might be.

I'm not a particular expert on this, it could be harmful or it could ultimately prove to be advantageous for things like long range shooting.
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hedwards: It likely would, the problem is that there isn't any certainty. That and we're not sure what the adaptation might be, how long it would take or if there's a population that couldn't handle it. We know that if we replace a body part with one that functions identically what we're dealing with, but if you substitute something that doesn't then it's really hard to say what the consequences of that might be.

I'm not a particular expert on this, it could be harmful or it could ultimately prove to be advantageous for things like long range shooting.
From the article, it seems they have done animal testing. Simulations and animals can only take one so far though. I imagine that's why the first human test was on someone who was going to die anyway. (As an aside his disease sounds like a truly horrible way to die. His poor family having to watch that ... no wonder his wife was emotional.) While naturally long-term effects of this new model can't be studied until it's put into someone longterm, current artificial hearts already have known limitations as stated in the article. So even with potential longterm deleterious effects (or beneficial ones as you yourself point out) it might still be an improvement over current models if not a panacea.

With anything new, regardless of how different or similar it is to the body's method of handling the function, one would hope the researchers would perform extensive testing before recommending widespread use. Although, in medical research, it is not unusual to cut studies short when for instance a drug shows huge beneficial effects for a deadly disease. Doctors, for obvious reasons, at that point will try to save the control group rather than let them continue to suffer and die. It does make it harder to study longterm effects of the drug, but it's rather harder to condemn the doctors and researchers for being human. It's definitely an ethical quandary for medical researchers and one which I'm very glad that as a basic science researcher I don't have to deal with.
Post edited December 01, 2011 by crazy_dave
I remember reading about doctors discovering that they needed to have life support systems cause a person to breath at a semi-random rate. (A person doesn't naturally breath in perfectly-timed intervals, and breathing too perfectly was deemed possibly harmful for the patient.) Perhaps they will discover something about this which needs altering or tweaking, but it sounds like a great idea, with plenty of potential. Just so long as they use something higher in quality than the cheap fans that go in most computers. (Assuming it uses fans/propellers.)
Post edited December 01, 2011 by EndlessKnight
Pretty cool, thanks for sharing, somehow I missed this one.

I am in favor of improving and reimagining the human body and other fields, biomimicry is not the 100% correct path... nature too has evolved over past mistakes, over erroneus branches; what if you could erase those little mistakes and make it even better? I say go for it. :)
Amazing story, op. I wonder if this device could prolong an otherwise healthy person's lifespan for a much longer time frame?