I have the "Venus in Furs" mission available, but when I enter the No-Tell Motel my screen goes black. I can feel my way around using the map so the game is still functional, just no video. If I back out of the motel the screen comes back.

I tried again the next time I started the game with another mission selected and got into the motel without incident, but as soon as I selected the mission to track which room to go to I lost the screen again.

Huh - Just reloaded the game with another mission active and fast traveled to outside the motel, found the door, seems to work. I'll have to come back to that as I'm in the middle of something else.

Wierd.

(2.01, without Phantom Liberty)

I think in the No-Tell Hotel I also had that, occurred to me once in the Konpeki Plaza. The solution was to change something in the graphics settings. Vsync on, maximum refresh rate 60Hz, but limit to 30. It was something like that.

This "mission" does not interrupt any other actions, so it can be played through on the side.

Thanks, will tinker. (Didn't happen on my first playthrough, no idea how many generations of patches have been applied since.)