I am running Wine on my mac (Snow Leopard macbook pro) and I was wondering what special configurations I would have to change for GOG to work on my computer. I tried running the setup file just like any other .exe on wine, and the installation window popped up in X11. The only problem is that when I tried to complete the installation, the only file that was actually installed was the desktop shortcut.
The specific game is Sid Meier's Alpha Centauri, but I was wondering if there would be a general solution.

I also am running Snow Leopard on a macbook pro. I use the program Wineskin to do all of my GOG installations/game running and have had great success with it so far. It's free to download.

http://wineskin.doh123.com/

According to AppDB, Alpha Centauri has some problems running under Wine in even the latest tests - one person says they managed to control the crashing, but others have not been so fortunate. Here is the settings of the person who says they controlled the crashing:

http://appdb.winehq.org/objectManager.php?sClass=version&iId=3647&iTestingId=64295