DrIstvaan: Thanks for trying to help, everyone.
@HampsterStyle
It's an ASUS M2E-MX motherboard. I know where to find its manual on-line, but thanks anyway. Also, this is not the first SATA drive we're adding to it.
@Jayded
In Boot order, I can only set in which order should the different devices be loaded (optical drive, then HDD, then floppy (yes, very likely we'll still use that, but anyway ;-))).
@Lexor
It is old, but not "ancient" (it was assembled at the end of 2007). It should be able to handle a 250GB HDD (given that there are already two or three /I can't say for sure if this is true for all/ HDDs which are at least that big).
Certain second-generation (3.0) SATA disk drives have issues with certain first-generation (many older motherboards with VIA or SIS chipsets) SATA controllers. This sounds like one of those problems. That makes the exact make and model of your motherboard and the exact make and model of your disk drive important.
M2E-MX is not a retail ASUS model number. Did this motherboard come out of a proprietary computer (Dell, HP, etc.)? Or is it M2A-MX or M2N-MX?
And what is the make and model of the disk drive you are trying to attach?