So my PC ran the game before on all high settings with Ubersampling disabled. Will an Nvidia 9800 GT run it on ANY settings or am I SOL? My fancy dual GPU graphics card went out, and this is the only one I'll be able to get my hands on for a while, as a friend is donating it.

9800 GT will play it just fine, just don't expect miracles from it. It will probably do best at medium or high settings and reduced resolution, not 1920x1080 but 1440x900 or 1280x720. Keeping the number of pixels that must be displayed down is a key to getting good performance out of minimum-spec cards like this one.

Also this thread will help you out a bit aswell.

http://www.gamefaqs.com/boards/975399-the-witcher-2-assassins-of-kings/59163248

Does anyone know how we can find the exact setup this game was created for? I know they test multiple settings and such but I would prefer the least amount of variation to ensure the least amount of bugs and trouble. My current PC is way out of date and I want to make sure the one I buy will run TW1 and TW2 perfectly. Also, besides hardware and hardware configuration settings, what about software? Even the anti-virus used and any modifications made to the testing PC would be greatly appreciated.

tl;dr: I would like a clone of the computer/accessories used by the designers of TW2/TW1 so that I can play the games without problems.