When I started ignoring games, dlcs and stuff I did it precisely as one of you pointed out above, to disable annoying games from popping out all the time on the main page. But then I got sort of curious and started ignoring items on that daily discovery queue. Then I realized that most of that stuff is garbage, so I got interested in understanding how much of the stuff on Steam is garbage, so I started with a massive ignore campaign :) (granted, a complete waste of time - and I was completely aware of that). Turns out, no surprises, that the wast majority of stuff on Steam is worthless, at least from my point of view :)
Having that said, out of cca 7000 items or so on GOG, currently, with all the items owned and having in mind the stuff I have on Steam and several other platform, I have a little over 40 items on my watchlist here, with the rest "blacklisted" through one addon :)
Of course, I should have read a book instead :)